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phenobarbital will minimize the extent or effect of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Potent or moderate CYP3A4 inducers may possibly increase price of diazepam elimination; hence, efficacy of diazepam could be lessened.Barbiturates are respiratory depressants, as well as diploma of respi